The human retinoblastoma gene (RB1) is imprinted; the mouse Rb1 gene is not.Imprinted expression of RB1 is due to differential methylation of a CpG island (CpG85), which is located in the pseudogene PPP1R26P1 in intron 2 of RB1.CpG85 serves as promoter for an alternative RB1 transcript, which is expressed from the unmethylated paternal allele only
Cordyceps militaris is an entomopathogenic fungus which is often used in Asia as a traditional medicine developed from age-old wisdom.Presently, cordycepin from C.militaris is a great interest in medicinal applications.However, cellular growth of C.militaris and the association with cordycepin production remain poorly understood.To explore the meta
The borderline indications between extraction and non-extraction treatment are not well defined in the orthodontics.The sagittal tooth movement for lengthening the tooth arch and space gaining should be considered with several aspects.Many authors have suggested appliances with combined action in several planes.In our opinion, it is very hard to ac